29/6/18: Have a look at TJ Ha's News & Views in Nature Photonics
21/6/18: Our collaboration with Helge Ewers applying iSCAT to living cells appears in BPJ
27/4/18: Our work on weighing single molecules with light is out in Science. Here is a perspective and more and more
10/4/18: Adam's paper on type IV pili dynamics is hosted on the bioRxiv
19/3/18: Christoph's paper on the photochemistry of vision comes to light in Nature Chemistry
7/12/17: The heroics of Gavin, Nik and many others appear on the bioRxiv. Weighing single molecules with light!
27/3/17: Gabi's paper on the bioRxivis highlighted on nanotechweb
2/1/17: Joanna's paper - cutting edge in Single-Molecule Biophysics by BPJ
18/1/17: Dan and Gavin's label-free single-molecule imaging in ACS Phototonics
3/1/17: Matz’s paper on retinal photo-isomerization is published in Nat. Chem.
Chris’ paper on vibronic microscopy is published in J. Phys. Chem. Lett.
Joanna’s paper on molecular motors is published in Methods in Enzymology
Jaime's paper on the origin of lifeis published in PNAS
Christoph's paper on channelrhodopsinis published in JACS
Jaime and Dan's paper on how to buildan iSCAT microscope appears in Nature Protocols
Ringing in the New Year with three papers:Kinesin dynamics in PNASSingle molecule optics in Nat. PhotonicsUltraprecise microtubule imaging in BPJ
1/10/15: Three papers in a week!Barrierless isomerisation of retinal in JACS, Coherent control of single molecules in JPCL and lipid nanodomain imaging in PNAS
Matz's paper on time-domain Raman is published in J. Phys. Chem. A
Gavin wins a partII thesis prize
Our work on dark-field microscopyis highlighted in an editorial and virtual issueon the international year of light
Christoph wins an EPSRC Doctoral Prize
Philipp wins the Marlow award from the Royal Society of Chemistry
Our work on singlet fission is published and highlighted in Nature Physics
Joanna's and Jaime's study of Myosin 5 published in eLife is highlighted by the Oxford Science and the APS Physics Buzz blogs
We are an interdisciplinary research group that develops and applies new optical methodologies to study (bio)molecular structure and dynamics. A particular focus rests on the use of light scattering to visualise and quantify the energetics and kinetics of biomolecular interactions all the way from small molecules to mesoscopic structures at the single molecule level. Central to these efforts is the universality of light scattering, making it applicable to all forms of matter and its close correlation with mass, which provides direct information on molecular identity. The result is a comparatively low-resolution combination of cryo-EM and native mass spectrometry, but with the distinct advantage of dynamic solution operation, single molecule sensitivity and imaging capability.